Established in 2008, the Crnic Institute is the first academic home for Down syndrome research in the United States. Funded through a collaboration between the University of Colorado School of Medicine, the University of Colorado Boulder, the Anna and John J. Sie Foundation and the Global Down Syndrome Foundation, the Crnic Institute is the only academic agency in the United States exclusively devoted to the study of Down syndrome.

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Tom Blumenthal, PHD

Executive Director Emeritus

Joaquín Espinosa, PhD

Executive Director

The Anna and John J. Sie Center for Down Syndrome


The Sie Center provides the highest quality of comprehensive care to children with Down syndrome and support for their families. Its experts coordinate medical care, speech, physical and other therapies, and educational support in order to ensure the best possible care for each child and adolescent with Down syndrome.


Clinical Director


The Rocky Mountain Alzheimer's Disease Center


The Rocky Mountain Alzheimer's Disease Center at the University of Colorado Anschutz Medical Campus is at the forefront of innovation in Alzheimer's disease research with a special focus on people with Down syndrome.

Johnathan Woodcock, Md

Clinical Director

Huntington Potter, PhD


Brianne Bettcher, PHD

Assistant Professor, Neuropsychologist