Trisomy 21 dysregulates T cell lineages toward an autoimmunity-prone state associated with interferon hyperactivity

This project took a deep dive into the T cell biology of people with Down syndrome. T cells are an important cell in the immune system. There are numerous types and subtypes of T cells, each with specific functions in the immune response. For example, “cytotoxic T cells” kill dangerous cells infected by virus or from tumors…..